Maple Grove, MN

763-494-9500

Boulder, CO

303-552-8722

Physiological Mechanisms of Acupuncture

Physiological Mechanisms of Acupuncture

(NIH, 1997): “Many studies in animals and humans have demonstrated that acupuncture can cause multiple biological responses. These responses can occur locally, i.e., at or close to the site of application, or at a distance, mediated mainly by sensory neurons to many structures within the central nervous system. This can lead to activation of pathways affecting various physiological systems in the brain as well as in the periphery.” A focus of attention has been the role of endogenous opioids in acupuncture analgesia. Considerable evidence supports the claim that opioid peptides are released during acupuncture and that the analgesic effects of acupuncture are at least partially explained by their actions. That opioid antagonists such as naloxone reverse the analgesic effects of acupuncture further strengthens this hypothesis. Stimulation by acupuncture may also

  1. Group III & Group IV afferent neurons (via substance P)
  2. CNS activation via HPA axis, homeostatic effect
  3. studied immune effects include stimulation of mast cell, bradykinin, cytokines
  4. needle insertion at specific segmental level (and via dermatomal distribution) stimulating CNS descending control mediates some of the immune response to acupuncture
  5. activate the hypothalamus and the pituitary gland, resulting in a broad spectrum of systemic effects,
  6. alter the secretion of neurotransmitters/neurohormones, regulate circulation & blood rheology, both centrally and peripherally,
  7. PET-Scans of the brain during acupuncture (Dold, 1998): University of California Irvine professor and physicist Zang-Hee Cho, a member of the National Academy of Science, inventor of an early version of the PET scanner and a pioneer of the MRI scanner, found that stimulation of the vision-related acupoint showed the same reaction in the brain as stimulation of the eye. As the acupuncture signal passes to the brain via nervous system, it possibly stimulates the hypothalamus, responsible for the production and release of hundreds of neurochemicals.
  8. Acupuncture: pain management coupled to immune stimulation (Gollub, 1999): “The phenomenon of acupuncture is both complex and dynamic. Recent information demonstrates that acupuncture may exert its actions on pain and immune processes. The coupling of these two systems occurs via common signaling molecules, i.e., opioid peptides. In this regard, we surmise that
      1. opioid activation leads to the processing of opioid peptides from their precursor, proenkephalin
      2. the simultaneous release of antibacterial peptides contained within the precursor as well.
      3. central nervous system pain circuits may be coupled to immune enhancement.
      4. Furthermore, acupuncture needle manipulation elicited signal increases bilaterally in the region of the primary and secondary somatosensory corticies in human brain as determined by magnetic resonance imaging.
      5. The maps reveal marked signal decreases bilaterally in multiple limbic and deep gray structures including the nucleus accumbens, amygdala, hypothalamus, hippocampus, and ventral tegmental area.

Taken together, we surmise a major central nervous system pathway as well as local pain and immune modulation during acupuncture.”

  1. (Fu, 2000): “In recent years, more and more laboratory proof has accumulated that acupuncture can
      1. change the charge and potential of neurons,
      2. the concentrations of K(+), Na(+), Ca(++) and
      3. the content of neuro-transmitters such as aspartate, and taurine and
      4. the quantities of neuro-peptides such as beta-endorphin and leu-enkephalin.
      5. All these phenomena are directly related to nerve cells.”
  2. Immune System effects of Acupuncture (Joos, 2002): “The following changes were found in the TCM group: within the lymphocyte subpopulations the CD3+ cells (p = 0.005) and CD4+ cells (p = 0.014) increased significantly. There were also significant changes in cytokine concentrations: interleukin (IL)-6 (p = 0.026) and IL-10 (p = 0.001) decreased whereas IL-8 (p = 0.050) rose significantly. Additionally, the in vitro lymphocyte proliferation rate increased significantly (p = 0.035) while the number of eosinophils decreased from 4.4% to 3.3% after acupuncture (p > 0.05). The control group, however, showed no significant changes apart from an increase in the CD4+ cells (p = 0.012).”
  3. Difference between Manual and Electro Acupuncture (Kong, 2002): “Results showed that electroacupuncture mainly produced fMRI signal increases in precentral gyrus, postcentral gyrus/inferior parietal lobule, and putamen/insula; in contrast, manual needle manipulation produced prominent decreases of fMRI signals in posterior cingulate, superior temporal gyrus, putamen/insula. These results indicate that different brain networks are involved during manual and electroacupuncture stimulation. It suggests that different brain mechanisms may be recruited during manual and electroacupuncture.”
  4. In Parkinson’s Disease (Wang L., 2002): “Under the auditory evoked brain stem potential (ABP) examination, the latent period of V wave and the intermittent periods of III-V peak and I-V peak were significantly shortened in Parkinson’s disease patients of the treatment group (N = 29) after acupuncture treatment. The difference of cumulative scores in Webster’s scale was also decreased in correlation analysis.”

Meet Our Practitioners:

I love this place! I saw Nicky and she truly feels for her patients. She is wonderful at what she does and makes it a great comfortable and peaceful place. She has helped me so much! I highly recommend her!

- Jessica

My experience with Modern Point Acupuncture has been outstanding.  I was treated by Nicky.  She has a warm and fun personality as well as a vast amount of knowledge.  Her passion for what she does is refreshing since I have been to many other acupuncturists where it is lacking. She truly wants to get to the root of the problem and get you pain relief.  I came to her with a severe antibiotic resistant sinus infection accompanied by chronic migraines.  After one session the pain went down drastically in my face and the migraines were improved.  After about two months of one or two appointments/week the migraines and sinus issues were gone and I was off all medications.  I would highly recommend anyone to her (Nicky), she is amazing at her craft.  Finding Modern Point Acupuncture has been such a blessing!

- C.M.

I have great news!! I'm PREGNANT! It is still hard for me to believe, and I cannot thank you enough! I strongly believe you had a very significant role in this good news :) and am incredibly thankful I came to see you Nicky! You are super great and I am so so happy I came to you!! THANK YOU again!

- B.C.

"I have horrible allergies and have tried acupuncture a little in the past but in the past the acupuncture was performed by a chiropractor. I went to see Lindsay once and then signed up for 10 sessions. It is amazing what acupuncture can do. My favorite is that it totally relaxes you and then you notice things during your day that it has helped with. Lindsay is extremely knowledgable and I have learned so much. It is amazing how certain parts of the body are tied to your eyes, brain, etc. If you have any type of issue go see Lindsay. She is great."

- Korrine

I'm so excited I get to do just that to tell you that I am pregnant!!!!  I just had my 8 week ultrasound today and baby looks good and healthy! Thank you so much for everything that you did for me Nicky! I appreciate it more than you know!

- B.R.

"Lindsay is a very caring and helpful person. She really cares about how her patients feel."

- Cassie

"Adam is the best! Not only is he awesome at what he does, he seems to be a genuinely nice human. He took the time to learn about my embarrassing condition and try to gear my treatment towards that. He was excited to learn about something he didn't know existed, and I very much appreciated that. I'd highly recommend seeing him! Thanks Adam!"

- Amanda D.